Effects of hemoglobin C and S traits on glycohemoglobin measurements by eleven methods.
نویسندگان
چکیده
globin Measurements by Eleven Methods, William L. Roberts, Sekineh Safar-Pour, Barun K. De, Curt L. Rohlfing, Cas W. Weykamp, and Randie R. Little ( Department of Pathology, ARUP Institute for Clinical & Experimental Pathology, University of Utah, Salt Lake City, UT; 2 ARUP Laboratories, Salt Lake City, UT; 3 Department of Pathology, University of Arizona, Tucson, AZ; 4 Departments of Pathology & Anatomical Sciences and Child Health, University of Missouri-Columbia School of Medicine, Columbia, MO; 5 Queen Beatrix Hospital, Winterswijk, The Netherlands; * address correspondence to this author at: ARUP Laboratories, 500 Chipeta Way, Salt Lake City, UT 84108; fax 801-584-5207, e-mail [email protected])
منابع مشابه
Increased fetal hemoglobin in insulin-treated diabetes mellitus contributes to the imprecision of glycohemoglobin measurements.
An increased prevalence of fetal hemoglobin (HbF) has been described in pediatric insulin-dependent patients. The popular electroendosmotic method for glycohemoglobin includes HbF. In an adult population comprising 50 insulin-treated and 57 non-insulin-treated diabetic patients and 57 control subjects, we measured HbF by HPLC and measured glycohemoglobin by both HPLC and an electroendosmotic me...
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of Use of Boronate Affinity Chromatography to Measure Glycohemoglobin in the Presence of Hemoglobin S and C Traits, Randie R. Little, Hubert Vesper, Curt L. Rohlfing, Maria Ospina, Sekineh Safar-Pour, and William L. Roberts ( University of Missouri-Columbia School of Medicine, Department of Pathology & Anatomical Sciences, Columbia, MO; 2 Centers for Disease Control and Prevention, Atlanta, GA;...
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BACKGROUND Diabetes mellitus is a major health problem worldwide with long-term micro- and macrovascular complications responsible for a majority of its morbidity and mortality. The development and progression of these complications relate strongly to glycemic control. METHODS We reviewed the literature extensively for studies that relate glycemic control to the development and progression of...
متن کاملScreening for hemoglobinopathies during routine hemoglobin A1c testing using the Tosoh G7 Glycohemoglobin Analyzer.
Approximately 5.1% of the US population has diabetes mellitus, and hemoglobin (Hb) A1c levels are routinely measured to monitor long-term glycemic control in these patients. Many laboratories use ion exchange chromatography for such measurements, and the presence of hemoglobin variants and hemoglobinopathies often results in abnormal peaks on the chromatogram. The goal of this study was to eval...
متن کاملEffects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin.
BACKGROUND Glycohemoglobin (gHb), measured as hemoglobin (Hb) A(1c) or as total gHb, provides a common means for assessing long-term glycemic control in individuals with diabetes mellitus. Genetic variants and chemically modified derivatives of Hb can profoundly affect the accuracy of these measurements, although effects vary considerably among commercially available methods. The prevalence of ...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 51 4 شماره
صفحات -
تاریخ انتشار 2005